Guatteria gaumeri MT

INTRODUCTION Guatteria gaumeri is a 10 to 15 m tall tree, with a blackish coloured bark. A homoeopathic mother tincture is prepared from dried bark of the plant. It is covered by Homoeopathic Pharmacopoeia of United States. Guatteria gaumeri acts on the liver and gallbladder, kidney and pancreas. It has affinity to improve digestive complaints with liver and biliary manifestation. It is one of the frequently used homoeopathic remedy for liver complaints. It is reported for gallstone. Its anti hypercholesterolemic effect was reported way back in 1982. 1 Studies have found that this is primarily due to its main component Alpha-asarone by decreasing the secretion of lipids. It is also found to be non-toxic. . 2 ,3 ,4 A clinical study has shown decrease in TC, LDL, VLDL, and increase in HDL.5 Indications : Liver malfunction, Hyperlipidaemia, etc. Schwabe’s Guatteria gaumeri Ø can be used alone or as supplement to other medicines.

Dosage : Unless otherwise prescribed, 10-20 drops 2-3 times a day, depending upon the caseIf complaints are not relieved, consult a specialist.

Side Effects : No side effects of Schwabe’s Guatteria gaumeri Ø are known in therapeutic doses.

Contraindications : No contra-indications for the use of Schwabe’s Guatteria gaumeri Ø are known.

Interactions : No interactions between Schwabe’s Guatteria gaumeri Ø and other products are known.

Presentation : Bottle of 30ml. 1 . Josefina Sanchez, Resendiz Angel, Lerdo de Tejada, Cholesterol-lowering effect of Guatteria gaumeri (preliminary report). Journal of Ethnopharmacology Volume 6, Issue 2, September 1982, Pages 239-242 2. Aarón Mendieta, Fabiola Jiménez, Leticia Garduño-Siciliano, Angélica Mojica-Villegas, Blanca Rosales-Acosta, Lourdes Villa-Tanaca, Germán Chamorro-Cevallos, José L.Medina-Franco, Nathalie Meurice, Rsuini U.Gutiérrez, Luisa E.Montiel, María del Carmen Cruz, Joaquín Tamariz, Synthesis and highly potent hypolipidemic activity of alpha-asarone- and fibrate-based 2-acyl and 2-alkyl phenols as HMG-CoA reductase inhibitors, Bioorganic & Medicinal Chemistry, Volume 22, Issue 21, 1 November 2014, Pages 5871-5882 3 . L.Rodríguez-Páez, M.Juárez-Sanchez, J.Antúnez-Solís, I.Baezaa C.Wong, α-Asarone inhibits HMG-CoA reductase, lowers serum LDL-cholesterol levels and reduces biliary CSI in hypercholesterolemic rats. Phytomedicine, Volume 10, Issue 5, 2003, Pages 397-404 4 . P.Morales-Ramírez, E.Madrigal-Bujaidar, J.Mercader-Martínez, M.Cassani, G.González, G.Chamorro-Cevallos, M.Salazar-Jacobo, Sister-chromatid exchange induction produced by in vivo and in vitro exposure to alpha-asarone. Mutation Research/Genetic Toxicology, Volume 279, Issue 4, 16 June 1992, Pages 269-273 5 . Aejaz Husain, Ashish Indani, Poonam Bhutada. Hypercholesterolemia effectively managed with homeopathic medicine Gautteria gaumeri (Yumel): results from a clinical study in academic clinical set up in north India. Int J Adv Med. 2017 Jun;4(3):772-777